mercredi 23 mars 2016

FROVATRIPTAN SUCCINATE Tablet, Film Coated [Glenmark Pharmaceuticals Inc., USA]


Frovatriptan Succinate Tablets

Read this Patient Information before you start taking frovatriptan succinate and each time you get a refill.  There may be new information. This information does not take the place of talking with your doctor.  You and your doctor should discuss frovatriptan succinate when you start taking your medication and at regular check-ups.

What is frovatriptan succinate?

Frovatriptan succinate is a prescription medicine used to treat migraine headaches with or without aura in adults.

Frovatriptan succinate is not used to treat other types of headaches.

Frovatriptan succinate is not used to prevent or decrease the number of migraine headaches.

It is not known if frovatriptan succinate is safe and effective to treat cluster headaches.

It is not known if frovatriptan succinate is safe and effective in children under 18 years of age.  

Who should not take frovatriptan succinate?

Do not take frovatriptan succinate if you have:

heart problems, a history of heart problems, or problems with the electrical system of your heart
had a stroke, transient ischemic attacks (TIAs), or problems with your blood circulation
hemiplegic migraines or basilar migraines.  If you are not sure if you have these types of migraines, ask your healthcare provider.
narrowing of blood vessels to your legs, arms, or stomach (peripheral vascular disease)
uncontrolled high blood pressure
taken any of the following medicines in the last 24 hours:
almotriptan (AXERT ®)
eletriptan (RELPAX ®)
naratriptan (AMERGE ®)
rizatriptan (MAXALT ®, MAXALT-MLT ®)
sumatriptan (IMITREX ®, SUMAVEL ® DosePro ®, ALSUMA ®)
sumatriptan and naproxen (TREXIMET ®)
zolmitriptan (ZOMIG ®)
Ergotamine or ergotamine-type medicines (BELLERGAL ®, CAFERGOT ®, ERGOMAR ®, WIGRAINE ®, D.H.E.45 ®, MIGRANAL ®, SANSERT ®)
Ask your healthcare provider if you are not sure if your medicine is listed above.
an allergy to frovatriptan or any of the ingredients in frovatriptan succinate.  See the end of this leaflet for a complete list of ingredients in frovatriptan succinate.

What should I tell my doctor before taking frovatriptan succinate?

Before you take frovatriptan succinate, tell your doctor about all of your medical conditions, including if you:

have high blood pressure
have high cholesterol
have diabetes
smoke
are overweight
are a female who has gone through menopause
have heart disease or a family history of heart disease or stroke
are pregnant or plan to become pregnant
are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Especially tell your doctor if you take:

propranolol
selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), two types of drugs for depression or other disorders.  Common SSRIs are CELEXA ® (citalopram HBr), LEXAPRO ® (escitalopram oxalate), PAXIL ® (paroxetine), PROZAC ®/SARAFEM ® (fluoxetine), SYMBAX ® (olanzapine/fluoxetine), ZOLOFT ® (sertraline), and fluvoxamine.  Common SNRIs are CYMBALTA ® (duloxetine) and EFFEXOR ® (venlafaxine).

These medicines may affect how frovatriptan succinate works, or frovatriptan succinate may affect how these medicines work.

Ask your doctor or pharmacist for a list of these medicines if you are not sure.

Know the medicines you take.  Keep a list of them to show your doctor or pharmacist when you get a new medicine.

How should I take frovatriptan succinate?

Certain people should take their first dose of frovatriptan succinate in their doctor’s office or in another medical setting.  Ask your doctor if you should take your first dose in a medical setting.
Take frovatriptan succinate exactly as your doctor tells you.
If you do not get any relief after your first frovatriptan succinate tablet, do not take a second tablet without first talking with your doctor.
If your headache comes back or you only get some relief from your headache, you may take a second frovatriptan succinate tablet 2 hours after the first tablet.
Do not take more than 3 frovatriptan succinate tablets in a 24-hour period.
It is not known if it is safe and effective to take frovatriptan succinate for more than 4 headaches in 30 days.
If you take too much frovatriptan succinate, call your doctor or go to the nearest hospital emergency room right away.
You should write down when you have headaches and when you take frovatriptan succinate so you can talk with your doctor about how frovatriptan succinate is working for you.

What should I avoid while taking frovatriptan succinate?

Frovatriptan succinate can cause dizziness, weakness, or drowsiness.  If you have these symptoms do not drive a car, use machinery, or do anything where you need to be alert.

What are the possible side effects of frovatriptan succinate?

Frovatriptan succinate can cause serious side effects.

Call your doctor right away if you have any of the following symptoms after taking frovatriptan succinate:

Heart attack or other heart problems.  Heart problems may lead to death. Stop taking frovatriptan succinate and get emergency medical help right away if you have any of the following symptoms of a heart attack or other heart problems:
Discomfort in the center of your chest that lasts for more than a few minutes, or that goes away and comes back
Chest pain or chest discomfort that feels like heavy pressure, squeezing, or fullness
Pain or discomfort in your arms, back, neck, jaw, or stomach
Shortness of breath with or without chest discomfort
Breaking out in a cold sweat
Feeling lightheaded
Nausea or vomiting with any of the symptoms included above
Stroke.  Symptoms of stroke include face drooping, slurred speech, and unusual weakness or numbness.
Changes in color or sensation in your fingers and toes (Raynaud’s syndrome).
Stomach and intestinal problems (gastrointestinal and colonic ischemic events). Symptoms of gastrointestinal and colonic ischemic events include:
Sudden or severe stomach pain
Stomach pain after meals
Weight loss
Nausea or vomiting
Constipation or diarrhea
Bloody diarrhea
Fever
Problems with blood circulation to your legs and feet (peripheral vacular ischemia). Symptoms of peripheral vascular ischemia include:
Cramping and pain in your legs or hips
Feeling of heaviness or tightness in your leg muscles
Burning or aching pain in your feet or toes while resting
Numbness, tingling, or weakness in your legs
Cold feeling or color changes in one or both legs or feet
Increased blood pressure
Allergic reactions.  Symptoms of allergic reaction include:
Rash
Hives
Itching
Swelling of the face, mouth, throat, or tongue
Difficulty breathing
Medication overuse headache. Some people who use too many frovatriptan succinate tablets may have worse headaches (medication overuse headache).  If your headaches get worse, your doctor may decide to stop your treatment with frovatriptan succinate.
Serotonin syndrome. Serotonin syndrome is a rare but serious problem that can happen in people using frovatriptan succinate, especially if frovatriptan succinate is used with anti-depressant medicines called SSRIs and SNRIs.  Call your doctor right away if you have any of the following symptoms of serotonin syndrome:
Mental changes such as seeing things that are not there (hallucinations), agitation, or coma
Fast heartbeat
Changes in blood pressure
High body temperature
Tight muscles
Trouble walking

The most common side effects of frovatriptan succinate are:

dizziness
fatigue (tiredness)
headache (other than a migraine headache)
paresthesia (feeling of tingling)
dry mouth
flushing (hot flashes)
feeling hot or cold
chest pain
dyspepsia (indigestion)
skeletal pain (pain in joints or bones)

Tell your doctor about any symptoms that you develop while taking frovatriptan succinate.

This is not a complete list of side effects.  Talk to your doctor if you develop any symptoms that concern you.

How should I store frovatriptan succinate?

Store frovatriptan succinate at 68° to 77°F (20° to 25°C). Protect frovatriptan succinate from moisture.  Discard after expiration date printed on package.

Keep frovatriptan succinate and all medicines out of the reach of children.

General advice about the safe and effective use of frovatriptan succinate.

Medicines are sometimes prescribed for conditions that are not mentioned in patient information leaflets.  Do not use frovatriptan succinate for a condition for which it was not prescribed. Do not give frovatriptan succinate to other people, even if they have the same symptoms as you. People may be harmed if they take medicines that have not been prescribed for them.

This leaflet summarizes the most important information about frovatriptan succinate. If you would like more information about frovatriptan succinate, talk to your doctor. You can ask your doctor or pharmacist for information on frovatriptan succinate that is written for healthcare professionals. You can also call Glenmark Pharmaceuticals Inc., USA at 1 (888)721-7115.

What are the Ingredients in frovatriptan succinate?

Active ingredient:  frovatriptan succinate

Inactive ingredients:  anhydrous lactose, colloidal silicon dioxide, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium starch glycolate (potato), talc, titanium dioxide and triacetin.

Manufactured by:

Glenmark Pharmaceuticals Ltd.
Plot No. 2, Phase-2, Pharma Zone SEZ
Pithampur, Dist.-Dhar
Madhya Pradesh 454775, India

Manufactured for:

Glenmark Pharmaceuticals Inc., USA
Mahwah, NJ 07430

Questions? 1(888)721-7115
http://ift.tt/1RAu82r

July 2015

Trademarks are the property of their respective owners.

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FROVATRIPTAN SUCCINATE Tablet, Film Coated [Glenmark Pharmaceuticals Inc., USA]

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