Caution is recommended in patients with a history of bipolar illness, as mood elevation is possible in this population.
Patients taking anticonvulsant medications should also exercise caution before taking this product, as folate may (i) interfere with anticonvulsant medication, and/or (ii) lower seizure threshold. Conversely, anticonvulsant medications may interfere with folate metabolism, although the exact mechanism of action is not clear or well understood.
Patients undergoing cancer treatment should consult their licensed medical practitioner for advice.
Folate alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient. Folate in doses above 0.1 mg daily may obscure pernicious anemia in that hematologic remission may occur while neurological manifestations progress.
Close ZOLATE (Folic Acid, Cholecalciferol) Capsule [Axiom Pharma]
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